Epithelial immunity and oral comlications of HIV/AIDS The genetic variation of innate immune genes with oral manifestations of HIV/AIDS
NIH/NIDCR R56 grant to investigate the realtionship of genetic variations in the defensin gene cluster and Toll-like receptors with the susceptibility and development of oral disease associated with HIV/AIDs (HPV, OHL, CA)
Defensin gene cluster variation and Candida carriage
The K23 mentored, patient oriented,clinical research grant involves the investigation and development of high-throughput genetic assays to study the complex genetic variations in the Defensin gene cluster with susceptibility to oral yesst infection in immunocompromised and non-immune compromised individuals. The defensins are epthelial expressed antimicrobial peptides involved with innate immume protection of mucosal surfaces. We are investigating the association of SNPs and CNVs with peptide expression and susceptibility to oral yeast infection in high risk patieints.
Oral Mucosal immunity in Vulnerable HIV infected Populations “The genetic variation of innate immune genes with oral manifestations of HIV”
NIH/NIDCR Program Project 1P01DE019759-01, The major goals for this program project is to identify variations within innate and adaptive immune defense mechanisms that may impact susceptibility and or progression of oral mucosal pathology associated with HIV/AIDS. Project 4 will focus on identifying possible genetic variations within the genes that impact innate and adaptive immunity.
Please note: only your personal physician or other health professional you consult can best advise you on matters of your health based on your medical history, your family medical history, your medication history, and how information from any of these databases may apply to you. Neither University of Cincinnati (NetWellness) nor any party involved in creating, producing or delivering this web site shall be liable for any damages arising out of access to or use of this web site, or any errors or omissions in the content thereof. (More)