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Alzheimer's Disease

Genetics of Alzheimer`s



What is the genetic tie in with Alzheimer`s? I am doing a research paper on this and need credible sources.


Genetic research has turned up evidence of a link between Alzheimer`s disease and genes on four chromosomes - 1, 14, 19 and 21. The apoE4 gene on chromosome 19 has been linked to late-onset Alzheimer`s disease(occurring after age 65), which is the most common form of the disease. Research has demonstrated that Alzheimer`s is not a single gene disorder. More than one gene mutation can cause AD and genes on multiple chromosomes are involved. Sometimes, two genes, one from each parent are needed for a person to get the disorder. Environmental factors must be considered, as well.

Related Resources:

Alzheimer's Disease Education and Referral Center
National Alzheimer's Association

For more information:

Go to the Alzheimer's Disease health topic, where you can:

Response by:

Jon Stuckey, PhD
Case Western Reserve University