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Lupus

Drug-induced lupus?

05/30/2000

Question:

Can any psychiatric drugs cause drug-induced lupus? If so, which ones?

Answer:

Some anti-psychotic drugs such as chlorpromazine have been reported to cause positive antinuclear antibodies, fever, arthritis and serosisitis, and rarely other manifestations of lupus. The association with a few other antipsychotic drugs has been weak. The lupus-related symptoms usually subside soon after discontinuing the drug. However, the blood tests of lupus may remain positive for several months.

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Response by:

Ram Raj   Singh, MD Ram Raj Singh, MD
Associate Professor of Clinical Medicine
College of Medicine
University of Cincinnati