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Wednesday, April 23, 2014
A drug developed by Dr. Gregory Guilford, principal scientist in Guilford research labs discovered a drug that regenerates damaged neurons. Have you heard any more information on this subject ? this would result in more than 90% recovery of Parkinsons. Thank you for your time.
A cure for Parkinson's is the holy grail of research in the field. The idea behind these drugs, including the one you mention, is allowing regeneration of neurons. These drugs are grouped under the category of Nerve Growth Factors. Most of these compounds are at the animal (mouse/monkey) stage of research. A similar approach has been tried in the setting of other neurological disorders in which cell death was an issue. For example, CNTF (a nerve growth factor) was tried in the setting of Lou-Gehrig's disease (ALS). While animal studies were promising, the human trial was a disappointment.
The moral of this story: we should be optimistic about a cure for Parkinson's disease, but in a cautious way. Until human studies are completed, it is premature to talk about a cure.
Arif Dalvi, MD
College of Medicine
University of Cincinnati