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Cancer Genetics

Normal Cell Transformation to Cancerous Cells



How do normal cells become cancerous?


There are over 50,000 genes in every cell of the body. Many of them are responsible for controlling the normal growth and life cycle of the cell. If one or, in many cases, multiple growth control genes are disrupted, the normal control mechanisms in the cell no longer work properly. The cell may grow in an uncontrolled fashion, producing a tumor. Additional gene changes may occur which allow even more growth and spread to other areas.

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Response by:

Judith A Westman, MD Judith A Westman, MD
Associate Professor, Clinical Internal Medicine, Pediatrics and Medical Biochemistry
College of Medicine
The Ohio State University