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NetWellness is a global, community service providing quality, unbiased health information from our partner university faculty. NetWellness is commercial-free and does not accept advertising.
Sunday, May 19, 2013
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NetWellness is a global, community service providing quality, unbiased health information from our partner university faculty. NetWellness is commercial-free and does not accept advertising.
Sunday, May 19, 2013
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Alzheimer's Disease |
Treatment with Aricept12/13/2000 |
If Aricept has been discontinued and a rapid decline has been noted, should Aricept be prescribed again? Thank you.
Hello! Thank you very much for submitting your question to us. Dr. Geldmacher, who is part of a team at the University Alzheimer Center has responded. "In general, a rapid decline after discontinuation of donepezil (Aricept) suggests that the medication was helping and should be resumed as early as possible. Some data suggest that declines that occur after discontinuing the medicine become irreversible by 6 weeks. In contrast, if no decline is noted within 6 weeks after discontinuation it is generally a safe assumption that the medication was no longer exerting clinically detectable efficacy, and can be safely stopped permanently. The same principles apply to the other drugs of this class, rivastigmine (Exelon) or galantamine (Reminyl -available only in Europe at this time)." Again, thank you very much for writing to us. If you have any further questions, please don`t hesitate to contact us again.
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Paula K Ogrocki, PhD Assistant Professor of Neurology School of Medicine Case Western Reserve University |
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David Geldmacher, MD Formerly, Assistant Professor of Neurology School of Medicine Case Western Reserve University |
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Please note: only your personal physician or other health professional you consult can best advise you on matters of your health based on your medical history, your family medical history, your medication history, and how information from any of these databases may apply to you. Neither University of Cincinnati (NetWellness) nor any party involved in creating, producing or delivering this web site shall be liable for any damages arising out of access to or use of this web site, or any errors or omissions in the content thereof. (More) 
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