Home HealthTopics Health Centers Reference Library Research
Join us on Facebook Join us on Facebook Share on Facebook

Parkinson's Disease

ADDING COMTAN(entacapone)



Neurologist has prescribed Comtan to be added to medications. Present meds are Sinemet 1800mg. daily: Mirapex 1.825 daily and Clozaril 25mg. daily Comtan is to be taken 3 times daily 25mg. each time. Question is: Should the Mirapex not be reduced as the new med. Comtan is introduced. Thanking you in anticipation of a speedy rreply.


Comtan will increase the delivery of Sinemet to you brain. As a result side effects such as hallucinations or dyskinesias are possible. If they do occur your doctor may reduce the dose of Mirapex and/or Sinemet. The exact adjustment should be discussed with your doctor.

For more information:

Go to the Parkinson's Disease health topic, where you can:

Response by:

Arif Dalvi, MD
Assistant Professor
College of Medicine
University of Cincinnati