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Infectious Diseases

Leischmaniasis.

08/13/2003

Question:

I would like information on the long term effect of the use of meglumine antimonate/sodium stibogluconate for a person treat for Leischmaniasis.

Answer:

Both compounds contain antimony. Meglumine is used only in Latin American and French-speaking countries. The major long-term side effect is kidney damage, but that is rare when the drugs are used in the proper dosage. There are many short term side effects including nausea, vomiting, muscle and joint aches, headache, and tiredness. There can be changes in heart rhythms especially in those who have underlying kidney disease. 

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Response by:

George S Deepe, Jr, MD George S Deepe, Jr, MD
Professor of Clinical Medicine
Director of Infectious Diseases
College of Medicine
University of Cincinnati