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Parkinson's Disease

Treatment for Steele Richardson disease

12/15/1998

Question:

I found a reference in an Irish medical journal stating that the Americans were trying a new treatment for Progressive Supra Nuclear Palsy (Steele Richardson disease) but can't find any place where an effective treatment is mentioned. Can you help?

Answer:

Due to the small number of patients with Progressive Supra Nuclear Palsy (Steele Richardson disease) there is little in the way of clinical trials. One trial that is underway is the use of newer dopamine agonists. My own clinical experience has been that it is difficult to achieve a good response without running into side effects such as hallucinations and confusion. The best bet remains a trial of Sinemet that may, in some patients, prove to be of modest benefit.

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Response by:

Arif Dalvi, MD
Assistant Professor
College of Medicine
University of Cincinnati