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HTLV Indeterminate With P24 Reactive.



I donated blood a few years ago and got a response back from the blood bank that my blood had tested positive for HTLV I/II antibodies, but subsequent supplemental tests came out negative. I discussed this with my doctor and decided to go for the HTML Western Blot test to test for HTLV antigens. The test came back as indeterminate. All antigens, except P24, were non-reactive. Now, I`ve had the ELISA test for HIV and it`s been negative. I also understand that HTLV and HIV share the p24 antigen.

I am originally from India (born and raised there) and I believe that HTLV is endemic there. Do I have a reason to be worried?


There is no reason to be concerned about an indeterminate test for HTLV I/II and any overlap with testing for HIV.

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Response by:

Judith   Feinberg, MD Judith Feinberg, MD
Professor of Medicine
College of Medicine
University of Cincinnati