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Skin Care and Diseases

De novo dysplasia

08/10/2006

Question:

Could you please tell me what de novo dysplasia is? Thanks.

Answer:

Webster's Collegiate Dictionary defines DeNovo as "over again".  Dysplasia is defined in Dorland's Medical Dictionary (25th edition) as "abnormality of development in pathology; alteration in size, shape and organization of adult cells".  I looked in several references but no specialty textbooks to find the phrase used in your question.  It would suggest that there is abnormality of cells within the epithelium of a given organ system, and it is repeating. 

It is imperative that you talk with you physician who may have a medical specialty use of this combination in this form.  That individual can clarify the way this was used in a given setting.

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Response by:

Charles L Heaton, MD
Professor
College of Medicine
University of Cincinnati