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Could a Certain Dietary Defficiency Cause Osteomalacia?



A 48 year old lady has a history of low back pain, and radiation of pain down right thigh for more than six months duration. X-rays showed signs suggesting osteomalacia and serum alkaline phosphatase was raised (185 U/L). Is this a primary problem due to dietary defficiency or could be secondary to some other pathology?


Osteomalacia can be the result of a number of conditions including vitamin D and/or calcium deficiency, renal disease, and certain medications.  A thorough evaluation would be necessary to determine the cause.

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Response by:

Margery   Gass, MD Margery Gass, MD
Formely, Professor, Clinical Obstetrics & Gynecology
College of Medicine
University of Cincinnati