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Arthritis and Rheumatism

Autobody Assay

07/19/2007

Question:

What autobody assay tests are used to diagnose lupus? Is there more than one test? And can other types of arthritis be diagnosed with antibody tests?

Answer:

The test most commonly used to screen for lupus is the ANA panel which includes the anti-nuclear antibody test and other more specific antibody tests. Having a positive test does not make the diagnosis of lupus. The positive test is only one of the criteria that may be used to make a diagnosis of lupus. The other antibody test used for diagnosis of arthritis is the anti-CCP antibody test for rheumatoid arthritis although again having the positive blood test does not make the diagnosis of rheumatoid arthritis. Most arthritis diagnoses are based on a group of criteria rather than a specific blood test.

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Response by:

Johnny  Su, MD Johnny Su, MD
Formerly, Assistant Professor of Medicine
School of Medicine
Case Western Reserve University