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Myasthenia Gravis

Collagen and hyaluronic facial fillers

09/20/2007

Question:

If botox injections for cosmetic purposes are not a good idea for people with MG, would collagen and/or the new Hyaluronic facial fillers (such as Restylane) be safe, please?

Thank you for your help.

Answer:

Botox works at the neuromuscular junction, the same site of disease activity as myasthenia, so it naturally can worsen the disease. I have found no papers or studies to indicate that the hyaluronic acid fillers cause problems with myasthenia gravis. As to their overall safety or usefulness for facial augmentation, I have no experience and can make no comment.

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Response by:

Robert W Neel, IV, MD Robert W Neel, IV, MD
Assistant Professor of Neurology
College of Medicine
University of Cincinnati