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Pulmonary Fibrosis

Please explain

09/18/2007

Question:

In my Mothers recent Radiology Report there is evidence of peripheral pulmonary fibrosis BUT also calcified granulomas of the spleen, Please explain --thank you

Answer:

Calcified granulomas in the spleen are common in many different conditions. In the Midwestern United States, previous histoplasmosis infection is a frequent cause. These are usually benign and rarely cause any symptoms in most patients. Peripheral fibrosis on an x-ray report can be a sign of interstitial lung disease. There are many different interstitial lung diseases and additional pulmonary evaluation is usually required in order to determine the cause. In most cases, pulmonary fibrosis and spleen calcifications are unrelated but on rare occasion, both can be caused by previous histoplasmosis or similar infection.

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Response by:

James N Allen, Jr, MD James N Allen, Jr, MD
Clinical Professor of Pulmonary, Allergy, Critical Care & Sleep Medicine
College of Medicine
The Ohio State University