Ask an Expert: Atypical junctional nevus

Skin Care and Diseases

Atypical junctional nevus
10/22/2007

Question:

What is atypical junctional nevus? My bf was just diagnosed as having it on his chest and wed like some info on it if possible....Thanks

Answer:

The definition varies depends on who is evaluating the biopsy/pathology specimen. The term is often used to describe either architectural or cell atypia within a mole. Architectural atypia (abnormal shape and structure of the mole under the microscope) alone is rarely concerning. However cytologic (cell) atypia, in which the cells have abnormal features within a mole, is of more concern and the lesion may require re-evaluation. For some patients, an atypical junctional nevus may just be a genetic marker of abnormal moles and a higher predisposition for melanoma elsewhere. For others, depending on the pathologist’s final reading, it may be a precancerous mole. You need to follow-up with your board certified dermatologist to get an idea of what the significance of this report is for your boyfriend.

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Response by:

Pranav Sheth, MD
Formerly:
College of Medicine
University of Cincinnati