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Mental Health

Seroquel treatment and carcinoid tumors



I am a cancer survivor (Carcinoid Tumors in the small intestines) and take Seroquel as treatment for Bipolar Disorder (I understand to help sleep and control voices). I am concerned about how Seroquel works, as I understand I should not use medications that could effect Serotonin because of my history with Carcinoid Tumors. Can you provide any information related to this concern?


There is very limited potential for exhibiting serotonin syndrome/side effects with quetiapine alone as a treatment, thus one could speculate limited potential for aggravating symptoms in patients with a history of carcinoid tumors.

Upon further review in the literature, I could not find any obvious relationship. As I stated, this could be different with combination therapy.

Hope this helps.

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Response by:

Nicholas A Votolato, RPh BCPP Nicholas A Votolato, RPh BCPP
Assistant Professor of Pharmacy
College of Pharmacy
Assistant Professor of Psychiatry, Emeritus
College of Medicine
The Ohio State University