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COPD (Chronic Obstructive Pulmonary Disease)

Spirometry results and the gas exchange box

04/08/2008

Question:

Hi I contacted you last week but unfortunately I was a little unsure of my test results. I had a spirometry done at my docs through being sob this reading was above normal for someone my age. Then I had one done at the hosp including the one in the glass box these were the findings. enclosed ps I have had another spirometry done at my docs since as he didnt really hold with the hospital results, and again this was normal. Do you think I have asthma emphysema or what, would appreciate your opinion I used to smoke between 7 -9 cigarettes a day for thirty years. I am 52 and female. What do you make of these please:- Pred LL PredUL Act1 %Pred

FEV1 (L) 2.67 3.91 3.00 91 FVC (L) 3.12 4.53 4.72 124 FEV 1 %FVC (%) 63.49 FEV 50 (L/s) 2.51 6.12 2.12 49 PEF (L/min)351.8 529.0 419.0 95 FEV1/VCmax %pred (%) 76.32 VC (L) 3.26 4.64 4.72 119 RV (L) 1.55 2.70 4.15 195 TLC (L) 5.23 7.21 8.87 143 RV % TLC (%) 27.08 46.20 46.79 128 ERV (L) 1.00 1.00 << << ITGV (L) 2.31 3.95 4.15 133 ITGV % TLC (%) 43.69 63.15 46.79 88 R tot (kPa*s/) 0.30 0.30 0.34 113 SG tot (1/(kPa*s)) 1.04 1.04 0.62 60

VA (L) 6.07 6.07 5.42 89 TLCO SB (mmol/min/KPa) 7.68 11.52 4.47 47 KCOc (mmol/min/kPa/L) -0.62 3.70 0.81 53

Answer:

Although it can sometimes be difficult to distinguish asthma from emphysema on pulmonary function tests, it appears that your TLCO SB is reduced at 47% of predicted.  If this is correct, this would be more consistent with emphysema than asthma.  You should discuss this further with your physician.

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Response by:

Mahasti   Rittinger, RRT Mahasti Rittinger, RRT
Clinical Program Manager of Pulmonary, Allergy, Critical Care & Sleep
College of Medicine
The Ohio State University

Phillip T Diaz, MD Phillip T Diaz, MD
Professor of Pulmonary, Allergy, Critical Care & Sleep Medicine
College of Medicine
The Ohio State University