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Prostate Cancer

Can Exposure to Herpes Virus Affect PSA?

01/15/2009

Question:

My boyfriend (age 60) has had a PSA of 4.5, then 3.9, but remaining stable. We are sexually active. I have herpes (no recent outbreaks) but he does not. Can the herpes virus affect his test results? And can sexual activity within 12-18 hours affect the reading?

Answer:

Exposure to Herpes virus does not raise the serum PSA.
Ejaculation within 48 hours prior to drawing the blood to do the PSA test may cause the PSA to be falsely abnormally elevated so I prefer that my patients wait until after 48 hours from the time of ejacultation to have their blood drawn for PSA.

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Response by:

R Bruce  Bracken, MD R Bruce Bracken, MD
Professor of Surgery
College of Medicine
University of Cincinnati