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Epilepsy

Long term use of phenytoin

01/21/2009

Question:

I had auras and my one one only seizure in 1991. I have been on 400mg of phenytoin taken once daily at night. What can you tell me about the long term negative effects of this level of phenytoin.

Answer:

Long term use of phenytoin may be associated with peripheral neuropathy (numbness in feet) or osteoporosis. Do not stop seizure medication without discussing with your health care provider.

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Response by:

David M Ficker, MD David M Ficker, MD
Associate Professor
College of Medicine
University of Cincinnati