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Prostate Cancer

Post Prostate Surgery PSA Level



My father-in-law had radical prostate surgery 11 years ago but has continued to receive various treatments and has been symptom free. Two months ago he had a PSA reading of 4 and just today he learned his PSA had doubled to 8. He was told to come back in a month for another PSA test. What is the most likely explanation for this? At this stage, what is the most likely prognosis and treatment?


He needs to be evaluated for likely recurrent disease. He will probably need a bone scan and maybe a pelvic CT scan. He should discuss with his doctor the possible role of adjuvant radiation and/or hormone therapy if appropriate for his case.

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Response by:

Lee E Ponsky, MD Lee E Ponsky, MD
Associate Professor of Urology
School of Medicine
Case Western Reserve University