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Combining allergy serum for injection



Is there any medical or statistical proof that separating different allergy serums into separate allergy injections at each medical visit is more beneficial or safer then combining serums into one serum per medical visit, if possible? Why do some allergists recommend giving six injections per office visit when other allergists recommend two injections per office visit for the same patient?


Allergen compatibility in mixtures has received much attention and research. Certain allergens such as mites and molds contain enzymes which can affect the potency of other allergens such as pollens or animal danders. However, usually this can be accomplished by mixtures of two or occasionally three vials. It is rarely necessary to prepare 6 vials.

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Response by:

I Leonard Bernstein, MD I Leonard Bernstein, MD
Clinical Professor Emeritus
College of Medicine
University of Cincinnati