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Wednesday, June 19, 2013
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NetWellness is a global, community service providing quality, unbiased health information from our partner university faculty. NetWellness is commercial-free and does not accept advertising.
Wednesday, June 19, 2013
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Tuberculosis |
Quantiferon TB Gold Blood Test02/10/2009 |
By having a history of +ppd x 10years, would the blood test be necessary? The blood test is now offered where I work. INH was taken. Chest x ray normal.
If you have had a positive tuberculin skin test or PPD in the past and completed latent TB infection treatment with isoniazid (INH) there is NO need for the QuantiFERON TB blood test. If you need serial or annual tuberculosis (TB) screening for work, you will need to continue to fill out the TB screening risk assessment for any signs or symptoms of active TB disease as per your institution’s employment protocol.
Currently there are two Interferon gamma release assays (IGRA) approved by the Food and Drug Administration (FDA) for the diagnosis of latent TB infection: The QuantiFERON-TB Gold Test and the TSpot TB Test. These blood tests measure the response to TB proteins when they are mixed with a small amount of blood.
The Centers for Control and Prevention (CDC) published a guideline for the TB blood test in Morbidity and Mortality Weekly Report in December 2005. An updated guideline is anticipated to be released soon. You can use an IGRA in anyone you would use the TST, however data are still lacking in several clinical circumstances including severely immunocompromised patients, patients at the extremes of age, and groups receiving periodic screening.
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Shu-Hua Wang, MD, MPH&TM Clinical Assistant Professor of Infectious Diseases Clinical Assistant Professor of The Division of Epidemiology College of Medicine The Ohio State University |
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Larry S Schlesinger, MD Professor: Molecular Virology, Immunology and Medical Genetics Microbiology Administration Environmental Health Sciences College of Medicine The Ohio State University |
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