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Diabetes

Actos & fatty liver

02/24/2009

Question:

does actose cause fatty liver.blood work did not show that until I was put on actose

Answer:

The medical problems for which actos would be prescribed represent situations where there is a high likelihood of developing fatty liver.  I don't know for sure but doubt that actos would cause diabetic fatty liver; however, drugs in the same class as actos have been associated with abnormal liver function tests.  Hence, it is not clear whether a valid distinction is being drawn between abnormalities that theoretically could be associated with either fatty liver or drug toxicity - it may be difficult to distinguish which is which.  An internal medicine, endocrinology or liver specialist may be helpful in sorting out these possibilities.

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Response by:

Robert M Cohen, MD Robert M Cohen, MD
Professor of Clinical Medicine
College of Medicine
University of Cincinnati