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Myasthenia Gravis

SFEMG and myasthenic crisis



is it possible to have a normal SFEMG during a myasthenic crisis or near-crisis. eg-when there is severe generalized weakness and respiratory difficulties with a concomitant drop in the MIP and vital capacity. if not what is the possible alternative diagnosis. and what further tests need to be done, in order to verify it.


No, it is not possible to have normal SFEMG in muscle weakened by MG. So if you have generalized weakness and a weak muscle showed normal SFEMG results, the cause is something else. There are other possibilities but it is not at all a good idea for me to speculate over the internet. The key is to work directly with an experienced neuromuscular specialist. An accurate diagnosis requires a solid doctor patient relationship. It is also always fine to get a second opinion.

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Response by:

John G Quinlan, MD John G Quinlan, MD
Professor of Neurology
College of Medicine
University of Cincinnati