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NetWellness is a global, community service providing quality, unbiased health information from our partner university faculty. NetWellness is commercial-free and does not accept advertising.
Wednesday, May 22, 2013
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NetWellness is a global, community service providing quality, unbiased health information from our partner university faculty. NetWellness is commercial-free and does not accept advertising.
Wednesday, May 22, 2013
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Sarcoidosis |
Sarcoidosis09/11/2009 |
my mother was diagnosed with neurosarcoid...she received high dose steroids and cytoxan with good response. Her prednisone was tapered, but she has been unable to come off the last 1-2 mg despite being on Imuran as well. Is Imuran the correct med or are more people perscribing cellcept. also, two other woman (caucasion/jewish/60`s) in her neighborhood have been dxed....are there any new studies about environment?
It is good that your mother is responding to the current therapy. The treatment for neurosarcoidosis is not well-defined. There are a number of case reports (anecdotes) relating to the use of Cellcept, cytoxan or anti-TNF drugs (e.g., Infliximab or thalidomide) for cases of neurosarcoidosis that are resistant to more conventional therapies, including prednisone and methotrexate. If cytoxan is working for her, it is a reasonable approach. She should be monitored for changes in her white blood count and for inflammation of the bladder (cystitis). The latter can be avoided using a drug called Mesna. It is not uncommon to require more than one drug to control neurosarcoidosis. If she only requires 1-2 mg of prednisone a day to help control the disease, this would be a relatively harmless treatment.
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Elliott D Crouser, MD Associate Professor of Pulmonary, Allergy, Critical Care & Sleep Medicine College of Medicine The Ohio State University |
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