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Wednesday, April 23, 2014
Janumet good for prediabetic ?
Is janumet once daily good for prediabetic person who has IGT with HbA1c around 8. Is this good drug I have information from web that the side effect profile is very low as compared to other drugs. My fasting remains 110 whereass my ppbs is less than 100.
Janumet is a brand name of a combination pill containing 2 medications: sitagliptin which raises the blood levels of the hormone glucagon-like peptide 1 and metformin which reduces the amount of sugar released by the liver. Metformin has been tested for the prevention of diabetes in people who would be classified now as pre-diabetes. To my knowledge sitagliptin has not been tested for this. It makes sense that this combination might be beneficial but I am not aware of studies which test it. Janumet would cost considerably more than metformin alone so that cost-benefit assessment would be important.
Robert M Cohen, MD
Professor of Clinical Medicine
College of Medicine
University of Cincinnati