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Im carrier of hemochromatosis as my dad had it and died of it and i would like to know when i have kids will they just be carrier or will they get it ? ive herd it affects boys more than gurls if i have boy will he get it or be carrier?


If you only have one mutation, there is a 50% chance that your child will inherit that mutation from you. The chance for your future children to have two mutations depends on whether your partner is a carrier or not. Your partner could have genetic testing to see if he has either of the two common mutations that cause hereditary hemochromatosis. If your partner is also a carrier, then the chance that your future children would inherit two mutations is 1 in 4, or 25%. If a person has two mutations, then they have the chance to develop signs and symptoms over their lifetime. Men tend to show symptoms earlier because women self-phlebotomize by having their monthly menstrual cycles.

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Response by:

Amy Curry Sturm, MS, LGC Amy Curry Sturm, MS, LGC
Associate Professor of Human Genetics
College of Medicine
The Ohio State University