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Lung diseases

Pulmonary Reactive Disease

06/23/2010

Question:

Is this related in any way to Alpha ! Antitrysin? What tests do they do to find out about PRD?

Answer:

I presume that your question refers to reactive airways disease and its potential relationship to Alpha 1-antitrypsin deficiency. Reactive airways disease is an asthma-like condition that classically is induced by an acute exposure to irritants such as chlorine gas. It can lead to long-term problems with overly sensitive airways leading to wheezing and shortness of breath. It is not directly linked to alpha 1-antitrypsin deficiency but is likely to manifest in patients suffering from underlying lung disease such as emphysema.

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Response by:

Mark D Wewers, MD Mark D Wewers, MD
Professor of Pulmonology, Allergy, Critical Care & Sleep
Molecular Virology, Immunology & Medical Genetics
Environmental Health Sciences
College of Medicine
The Ohio State University