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Pharmacy and Medications

Lisinopril and Diuretic Together



I take 5mg lisiniprol for hypertension. Can I take an over the counter diurectic without harm?


Thank you for contacting Net Wellness. Diuretics can be used to treat hypertension as well as bloating symptoms. However, there are some alternative therapies for bloating symptoms other than diuretics such as: natural food (i.e. asparagus), exercise, proper sleep, and decreasing sodium intake. 

Non-pharmacologic therapies to help lower blood pressure include: eating a low-sodium diet, exercise, smoking cessation, and weight loss. Using these forms of non-pharmacologic treatments can be safer than using an over-the-counter diuretic because it is a long-term solution to the problem at hand. 

Lisinopril is a drug that is commonly used for hypertension, but it may also lead to electrolyte imbalances, such as an increase in potassium. This is why your prescribing physician most likely does routine lab draws to monitor your electrolytes. While diuretics can also be used for bloating symptoms and an additive agent for hypertension, it can also lead to electrolyte imbalances. This may be unsafe to take with lisinopril for reasons such as an unsafe drop in blood pressure and electrolyte imbalances. If electrolyte imbalances become severe, it can lead to life-threatening complications. Because of this, your doctor should be aware of all of the medications you are taking, including over-the-counter medications. 

Before buying an over-the-counter diuretic, I highly suggest talking with your primary care provider to select a therapy that is safe to take with your other medical conditions. 

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Response by:

Sarah Hudson-DiSalle, PharmD, RPh
Specialty Practice Pharmacist of Outpatient Pharmacy
College of Medicine
The Ohio State University